RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy

BACKGROUND: Critical illness myopathy (CIM) is associated with severe skeletal muscle wasting and impaired function in intensive care unit (ICU) patients. The mechanisms underlying CIM remain incompletely understood. To elucidate the biological activities occurring at the transcriptional level in th...

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Detalles Bibliográficos
Autores principales: Llano-Diez, Monica, Fury, Wen, Okamoto, Haruka, Bai, Yu, Gromada, Jesper, Larsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466682/
https://www.ncbi.nlm.nih.gov/pubmed/30992050
http://dx.doi.org/10.1186/s13395-019-0194-1

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