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Leveraging the effects of chloroquine on resistant malaria parasites for combination therapies

BACKGROUND: Malaria is a major global health problem, with the Plasmodium falciparum protozoan parasite causing the most severe form of the disease. Prevalence of drug-resistant P. falciparum highlights the need to understand the biology of resistance and to identify novel combination therapies that...

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Detalles Bibliográficos
Autores principales: Untaroiu, Ana M., Carey, Maureen A., Guler, Jennifer L., Papin, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466727/
https://www.ncbi.nlm.nih.gov/pubmed/30987583
http://dx.doi.org/10.1186/s12859-019-2756-y