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Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector
BACKGROUND: A robust scalable method for producing enucleated red blood cells (RBCs) is not only a process to produce packed RBC units for transfusion but a potential platform to produce modified RBCs with applications in advanced cellular therapy. Current strategies for producing RBCs have shortcom...
Autores principales: | Mayers, Steven, Moço, Pablo Diego, Maqbool, Talha, Silva, Pamuditha N., Kilkenny, Dawn M., Audet, Julie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466758/ https://www.ncbi.nlm.nih.gov/pubmed/30987611 http://dx.doi.org/10.1186/s12896-019-0515-9 |
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