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MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway

BACKGROUND: Intervertebral disc degeneration (IDD) is a major contributor to back, neck, and radicular pain, and the treatment of IDD is costly and relatively ineffective. Dysregulation of microRNAs (miRNAs) has been reported to be involved in IDD. The purpose of our study is to illustrate the poten...

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Detalles Bibliográficos
Autores principales: Yang, Qi, Guo, Xiao-Peng, Cheng, Yan-Li, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769/
https://www.ncbi.nlm.nih.gov/pubmed/30987676
http://dx.doi.org/10.1186/s13075-019-1863-5