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Estrogen regulation of cardiac cAMP-L-type Ca(2+) channel pathway modulates sex differences in basal contraction and responses to β(2)AR-mediated stress in left ventricular apical myocytes

BACKGROUNDS/AIM: Male and female hearts have many structural and functional differences. Here, we investigated the role of estrogen (E2) in the mechanisms of sex differences in contraction through the cAMP-L-type Ca(2+)channel pathway in adult mice left ventricular (LV) apical myocytes at basal and...

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Detalles Bibliográficos
Autores principales:	Machuki, Jeremiah Ong’achwa, Zhang, Hong-Yuan, Geng, Juan, Fu, Lu, Adzika, Gabriel Komla, Wu, Lijuan, Shang, Wenkang, Wu, Jinxia, Kexue, Li, Zhao, Zhiwei, Sun, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466778/ https://www.ncbi.nlm.nih.gov/pubmed/30987657 http://dx.doi.org/10.1186/s12964-019-0346-2

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