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Acute Leukemia Induces Senescence and Impaired Osteogenic Differentiation in Mesenchymal Stem Cells Endowing Leukemic Cells with Functional Advantages

Mesenchymal stem cells (MSC) constitute an important cell population of the bone marrow hematopoietic niche that supports normally hematopoietic stem cells (HSC) but eventually also leukemic cells. The alterations that occur in the MSC under leukemic stress are not well known. To deepen on this topi...

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Detalles Bibliográficos
Autores principales: Bonilla, Ximena, Vanegas, Natalia-Del Pilar, Vernot, Jean Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466857/
https://www.ncbi.nlm.nih.gov/pubmed/31065273
http://dx.doi.org/10.1155/2019/3864948