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Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease
Uromodulin, the most abundant protein in urine, is synthesized in the thick ascending loop of Henle and distal convoluted tubules. Patients with chronic kidney disease (CKD) have reduced urinary uromodulin levels secondary to tubular damage. Genome wide association studies identified significant sin...
Autores principales: | Nqebelele, Nolubabalo Unati, Dickens, Caroline, Dix-Peek, Therese, Duarte, Raquel, Naicker, Saraladevi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466913/ https://www.ncbi.nlm.nih.gov/pubmed/31065383 http://dx.doi.org/10.1155/2019/8094049 |
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