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Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease

Uromodulin, the most abundant protein in urine, is synthesized in the thick ascending loop of Henle and distal convoluted tubules. Patients with chronic kidney disease (CKD) have reduced urinary uromodulin levels secondary to tubular damage. Genome wide association studies identified significant sin...

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Detalles Bibliográficos
Autores principales: Nqebelele, Nolubabalo Unati, Dickens, Caroline, Dix-Peek, Therese, Duarte, Raquel, Naicker, Saraladevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466913/
https://www.ncbi.nlm.nih.gov/pubmed/31065383
http://dx.doi.org/10.1155/2019/8094049

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