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Comparative Study of Chemical Stability of Two H(1) Antihistaminic Drugs, Terfenadine and Its In Vivo Metabolite Fexofenadine, Using LC-UV Methods
A comparative study of chemical stability of terfenadine (TER) and its in vivo metabolite fexofenadine (FEX) was performed. Both TER and FEX were subjected to high temperature at different pH and UV/VIS light at different pH and then quantitatively analyzed using new validated LC-UV methods. These m...
Autores principales: | Gumieniczek, Anna, Berecka-Rycerz, Anna, Pietraś, Rafał, Kozak, Izabela, Lejwoda, Karolina, Kozyra, Paweł |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466962/ https://www.ncbi.nlm.nih.gov/pubmed/31061743 http://dx.doi.org/10.1155/2019/5790404 |
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