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The search for a PKR code—differential regulation of protein kinase R activity by diverse RNA and protein regulators
The interferon-inducible protein kinase R (PKR) is a key component of host innate immunity that restricts viral replication and propagation. As one of the four eIF2α kinases that sense diverse stresses and direct the integrated stress response (ISR) crucial for cell survival and proliferation, PKR&#...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467004/ https://www.ncbi.nlm.nih.gov/pubmed/30770398 http://dx.doi.org/10.1261/rna.070169.118 |