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Poly-ICLC, a TLR3 Agonist, Induces Transient Innate Immune Responses in Patients With Treated HIV-Infection: A Randomized Double-Blinded Placebo Controlled Trial

Objective: Toll-like receptor-3 agonist Poly-ICLC has been known to activate immune cells and induce HIV replication in pre-clinical experiments. In this study we investigated if Poly-ICLC could be used for disrupting HIV latency while simultaneously enhancing innate immune responses. Design: This w...

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Detalles Bibliográficos
Autores principales: Saxena, Mansi, Sabado, Rachel L., La Mar, Melissa, Mohri, Hiroshi, Salazar, Andres M., Dong, Hanqing, Correa Da Rosa, Joel, Markowitz, Martin, Bhardwaj, Nina, Miller, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467168/
https://www.ncbi.nlm.nih.gov/pubmed/31024557
http://dx.doi.org/10.3389/fimmu.2019.00725