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Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension

INTRODUCTION: Skeletal muscle dysfunction is a clinically important complication of pulmonary arterial hypertension (PAH). Growth/differentiation factor 15 (GDF-15), a prognostic marker in PAH, has been associated with muscle loss in other conditions. We aimed to define the associations of GDF-15 an...

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Detalles Bibliográficos
Autores principales:	Garfield, Benjamin E, Crosby, Alexi, Shao, Dongmin, Yang, Peiran, Read, Cai, Sawiak, Steven, Moore, Stephen, Parfitt, Lisa, Harries, Carl, Rice, Martin, Paul, Richard, Ormiston, Mark L, Morrell, Nicholas W, Polkey, Michael I, Wort, Stephen John, Kemp, Paul R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Skeletal Muscle
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467240/ https://www.ncbi.nlm.nih.gov/pubmed/30554141 http://dx.doi.org/10.1136/thoraxjnl-2017-211440

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