Cargando…

Sputum exosomes: promising biomarkers for idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease of unknown aetiology which leads rapidly to death. As diagnosis of IPF is complex, we aimed to characterise microRNA (miRNA) content of exosomes from sputum of patients with IPF. Using miRNA quantitative PCR arr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Njock, Makon-Sébastien, Guiot, Julien, Henket, Monique A, Nivelles, Olivier, Thiry, Marc, Dequiedt, Franck, Corhay, Jean-Louis, Louis, Renaud E, Struman, Ingrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467246/ https://www.ncbi.nlm.nih.gov/pubmed/30244194 http://dx.doi.org/10.1136/thoraxjnl-2018-211897

Ejemplares similares

Macrophage-derived exosomes attenuate fibrosis in airway epithelial cells through delivery of antifibrotic miR-142-3p
por: Guiot, Julien, et al.
Publicado: (2020)

A Blood Exosomal miRNA Signature in Acute Respiratory Distress Syndrome
por: Parzibut, Gilles, et al.
Publicado: (2021)

Exosomal miRNAs in Lung Diseases: From Biologic Function to Therapeutic Targets
por: Guiot, Julien, et al.
Publicado: (2019)

Systematic review of overlapping microRNA patterns in COVID-19 and idiopathic pulmonary fibrosis
por: Guiot, Julien, et al.
Publicado: (2023)

Blood Biomarkers in Idiopathic Pulmonary Fibrosis
por: Guiot, Julien, et al.
Publicado: (2017)

Endothelial extracellular vesicles promote tumour growth by tumour‐associated macrophage reprogramming
por: Njock, Makon‐Sébastien, et al.
Publicado: (2022)

Combined obstructive airflow limitation associated with interstitial lung diseases (O-ILD): the bad phenotype ?
por: Guiot, Julien, et al.
Publicado: (2022)

Exosomal Long Non-Coding RNAs in Lung Diseases
por: Poulet, Christophe, et al.
Publicado: (2020)

A new nucleosomic-based model to identify and diagnose SSc-ILD
por: Guiot, Julien, et al.
Publicado: (2020)

Serum IGFBP-2 in systemic sclerosis as a prognostic factor of lung dysfunction
por: Guiot, Julien, et al.
Publicado: (2021)

Altered epigenetic features in circulating nucleosomes in idiopathic pulmonary fibrosis
por: Guiot, J., et al.
Publicado: (2017)

Sputum biomarkers in IPF: Evidence for raised gene expression and protein level of IGFBP-2, IL-8 and MMP-7
por: Guiot, J., et al.
Publicado: (2017)

Increased KL-6 levels in moderate to severe COVID-19 infection
por: Cambier, Maureen, et al.
Publicado: (2022)

Raised serum levels of IGFBP-1 and IGFBP-2 in idiopathic pulmonary fibrosis
por: Guiot, J., et al.
Publicado: (2016)

The Lung Microbiome in Idiopathic Pulmonary Fibrosis: A Promising Approach for Targeted Therapies
por: Fastrès, Aline, et al.
Publicado: (2017)

Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels
por: O’Grady, Tina, et al.
Publicado: (2022)

Editorial: Progressive fibrosing interstitial lung disease: from bench to bedside
por: Guiot, Julien, et al.
Publicado: (2023)

Airflow obstruction as a marker of adverse prognosis in rheumatoid arthritis
por: Guiot, Julien, et al.
Publicado: (2023)

Reduced sputum expression of interferon-stimulated genes in severe COPD
por: Hilzendeger, Clarissa, et al.
Publicado: (2016)

Increased of exhaled breath condensate neutrophil chemotaxis in acute exacerbation of COPD
por: Corhay, Jean Louis, et al.
Publicado: (2014)

Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?
por: Demarche, Sophie, et al.
Publicado: (2016)

Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation
por: Schleich, Florence N, et al.
Publicado: (2013)

Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer
por: Bovy, Nicolas, et al.
Publicado: (2015)

Inflammatory profile of induced sputum composition in systemic sclerosis and comparison with healthy volunteers
por: Jacquerie, P., et al.
Publicado: (2021)

YKL-40 as a new promising prognostic marker of severity in COVID infection
por: Schoneveld, Lauranne, et al.
Publicado: (2021)

Is it possible to claim or refute sputum eosinophils ≥ 3% in asthmatics with sufficient accuracy using biomarkers?
por: Demarche, Sophie F., et al.
Publicado: (2017)

Extracellular Vesicles Mediate Communication between Endothelial and Vascular Smooth Muscle Cells
por: Fontaine, Marie, et al.
Publicado: (2021)

Benralizumab in severe eosinophilic asthma in real life: confirmed effectiveness and contrasted effect on sputum eosinophilia versus exhaled nitric oxide fraction – PROMISE
por: Schleich, Florence, et al.
Publicado: (2023)

Biomarkers in systemic sclerosis-associated interstitial lung disease: review of the literature
por: Bonhomme, Olivier, et al.
Publicado: (2019)

Effectiveness of inhaled corticosteroids in real life on clinical outcomes, sputum cells and systemic inflammation in asthmatics: a retrospective cohort study in a secondary care centre
por: Demarche, Sophie F, et al.
Publicado: (2017)

Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping
por: Schleich, F., et al.
Publicado: (2021)

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes
por: Blomme, Arnaud, et al.
Publicado: (2016)

Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic
por: Guiot, J., et al.
Publicado: (2020)

White Blood Cells in Patients Treated with Programmed Cell Death-1 Inhibitors for Non-small Cell Lung Cancer
por: Sibille, A., et al.
Publicado: (2021)

Airway Macrophages Encompass Transcriptionally and Functionally Distinct Subsets Altered by Smoking
por: Liégeois, Maude, et al.
Publicado: (2022)

Exploring the RNA landscape of endothelial exosomes
por: Pérez-Boza, Jennifer, et al.
Publicado: (2018)

Sputum IgE and Cytokines in Asthma: Relationship with Sputum Cellular Profile
por: Manise, Maïté, et al.
Publicado: (2013)

AI-Based Chest CT Analysis for Rapid COVID-19 Diagnosis and Prognosis: A Practical Tool to Flag High-Risk Patients and Lower Healthcare Costs
por: Esposito, Giovanni, et al.
Publicado: (2022)

Noncoding RNAs regulate NF-κB signaling to modulate blood vessel inflammation
por: Cheng, Henry S., et al.
Publicado: (2014)

Progressive fibrosing interstitial lung disease in rheumatoid arthritis: A retrospective study
por: Denis, Anna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_op12t9gi2lvpmsasgu3j5pa5r1