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Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study

BACKGROUND: A nonsputum blood test capable of predicting progression of healthy individuals to active tuberculosis (TB) before clinical symptoms manifest would allow targeted treatment to curb transmission. We aimed to develop a proteomic biomarker of risk of TB progression for ultimate translation...

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Detalles Bibliográficos
Autores principales:	Penn-Nicholson, Adam, Hraha, Thomas, Thompson, Ethan G., Sterling, David, Mbandi, Stanley Kimbung, Wall, Kirsten M., Fisher, Michelle, Suliman, Sara, Shankar, Smitha, Hanekom, Willem A., Janjic, Nebojsa, Hatherill, Mark, Kaufmann, Stefan H. E., Sutherland, Jayne, Walzl, Gerhard, De Groote, Mary Ann, Ochsner, Urs, Zak, Daniel E., Scriba, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467365/ https://www.ncbi.nlm.nih.gov/pubmed/30990820 http://dx.doi.org/10.1371/journal.pmed.1002781

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