Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

Sleep disordered breathing (SDB)-related overnight hypoxemia is associated with cardiometabolic disease and other comorbidities. Understanding the genetic bases for variations in nocturnal hypoxemia may help understand mechanisms influencing oxygenation and SDB-related mortality. We conducted genome...

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Detalles Bibliográficos
Autores principales: Cade, Brian E., Chen, Han, Stilp, Adrienne M., Louie, Tin, Ancoli-Israel, Sonia, Arens, Raanan, Barfield, Richard, Below, Jennifer E., Cai, Jianwen, Conomos, Matthew P., Evans, Daniel S., Frazier-Wood, Alexis C., Gharib, Sina A., Gleason, Kevin J., Gottlieb, Daniel J., Hillman, David R., Johnson, W. Craig, Lederer, David J., Lee, Jiwon, Loredo, Jose S., Mei, Hao, Mukherjee, Sutapa, Patel, Sanjay R., Post, Wendy S., Purcell, Shaun M., Ramos, Alberto R., Reid, Kathryn J., Rice, Ken, Shah, Neomi A., Sofer, Tamar, Taylor, Kent D., Thornton, Timothy A., Wang, Heming, Yaffe, Kristine, Zee, Phyllis C., Hanis, Craig L., Palmer, Lyle J., Rotter, Jerome I., Stone, Katie L., Tranah, Gregory J., Wilson, James G., Sunyaev, Shamil R., Laurie, Cathy C., Zhu, Xiaofeng, Saxena, Richa, Lin, Xihong, Redline, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467367/
https://www.ncbi.nlm.nih.gov/pubmed/30990817
http://dx.doi.org/10.1371/journal.pgen.1007739

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