Cargando…

Import of extracellular ATP in yeast and man modulates AMPK and TORC1 signalling

AMP-activated kinase (AMPK) and target of rapamycin (TOR) signalling coordinate cell growth, proliferation, metabolism and cell survival with the nutrient environment of cells. The poor vasculature and nutritional stress experienced by cells in solid tumours raises the question: how do they assimila...

Descripción completa

Detalles Bibliográficos
Autores principales:	Forte, Gabriella M., Davie, Elizabeth, Lie, Shervi, Franz-Wachtel, Mirita, Ovens, Ashley J., Wang, Tingting, Oakhill, Jonathan S., Maček, Boris, Hagan, Iain M., Petersen, Janni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467490/ https://www.ncbi.nlm.nih.gov/pubmed/30814334 http://dx.doi.org/10.1242/jcs.223925

Ejemplares similares

Nitrogen Regulates AMPK to Control TORC1 Signaling
por: Davie, Elizabeth, et al.
Publicado: (2015)

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress
por: Ling, Naomi X.Y., et al.
Publicado: (2020)

The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1
por: Lie, Shervi, et al.
Publicado: (2019)

A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans
por: Halova, Lenka, et al.
Publicado: (2021)

Ste12/Fab1 phosphatidylinositol-3-phosphate 5-kinase is required for nitrogen-regulated mitotic commitment and cell size control
por: Cobley, David, et al.
Publicado: (2017)

Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2
por: Du, Wei, et al.
Publicado: (2016)

TOR complex 2 localises to the cytokinetic actomyosin ring and controls the fidelity of cytokinesis
por: Baker, Karen, et al.
Publicado: (2016)

The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity
por: Lie, Shervi, et al.
Publicado: (2018)

Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7
por: Frey, Yannick, et al.
Publicado: (2022)

FH3, A Domain Found in Formins, Targets the Fission Yeast Formin Fus1 to the Projection Tip During Conjugation
por: Petersen, Janni, et al.
Publicado: (1998)

TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast
por: Du, Wei, et al.
Publicado: (2012)

WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy
por: Bakula, Daniela, et al.
Publicado: (2017)

AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1
por: Doshi, Heena, et al.
Publicado: (2023)

The neuropeptide complement of the marine annelid Platynereis dumerilii
por: Conzelmann, Markus, et al.
Publicado: (2013)

Control of Morphological Differentiation of Streptomyces coelicolor A3(2) by Phosphorylation of MreC and PBP2
por: Ladwig, Nils, et al.
Publicado: (2015)

Xenacoelomorph Neuropeptidomes Reveal a Major Expansion of Neuropeptide Systems during Early Bilaterian Evolution
por: Thiel, Daniel, et al.
Publicado: (2018)

Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin
por: Morrison, Kaitlin R., et al.
Publicado: (2023)

Histone 4 lysine 5/12 acetylation enables developmental plasticity of Pristionchus mouth form
por: Werner, Michael S., et al.
Publicado: (2023)

Author Correction: Histone 4 lysine 5/12 acetylation enables developmental plasticity of Pristionchus mouth form
por: Werner, Michael S., et al.
Publicado: (2023)

The Integrin Activating Protein Kindlin-3 Is Cleaved in Human Platelets during ST-Elevation Myocardial Infarction
por: Kraemer, Bjoern F., et al.
Publicado: (2019)

Snf1/AMPK promotes the formation of Kog1/Raptor-bodies to increase the activation threshold of TORC1 in budding yeast
por: Hughes Hallett, James E, et al.
Publicado: (2015)

Heat-Shock Protein 27 (HSPB1) Is Upregulated and Phosphorylated in Human Platelets during ST-Elevation Myocardial Infarction
por: Kraemer, Bjoern F., et al.
Publicado: (2019)

The Tyrosine-Autokinase UbK Is Required for Proper Cell Growth and Cell Morphology of Streptococcus pneumoniae
por: Pelletier, Anaïs, et al.
Publicado: (2019)

A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins
por: Drwesh, Layla, et al.
Publicado: (2022)

Nemertean, Brachiopod, and Phoronid Neuropeptidomics Reveals Ancestral Spiralian Signaling Systems
por: Thiel, Daniel, et al.
Publicado: (2021)

Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator
por: Ovens, Ashley J., et al.
Publicado: (2022)

Identifying components required for OMP biogenesis as novel targets for antiinfective drugs
por: Weirich, Johanna, et al.
Publicado: (2017)

An Unprecedented Tolerance to Deletion of the Periplasmic Chaperones SurA, Skp, and DegP in the Nosocomial Pathogen Acinetobacter baumannii
por: Birkle, Karolin, et al.
Publicado: (2022)

Extracellular Matrix-Specific Platelet Activation Leads to a Differential Translational Response and Protein De Novo Synthesis in Human Platelets
por: Kraemer, Bjoern F., et al.
Publicado: (2020)

AMPK suppresses Th2 cell responses by repressing mTORC2
por: Pandit, Mahesh, et al.
Publicado: (2022)

Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants
por: Hanzelmann, Dennis, et al.
Publicado: (2016)

Cytosolic Hsp70 and Hsp40 chaperones enable the biogenesis of mitochondrial β-barrel proteins
por: Jores, Tobias, et al.
Publicado: (2018)

The integral spliceosomal component CWC15 is required for development in Arabidopsis
por: Slane, Daniel, et al.
Publicado: (2020)

TORC1-Dependent Phosphorylation Targets in Fission Yeast
por: Otsubo, Yoko, et al.
Publicado: (2017)

TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2
por: Zhang, Zhiyong, et al.
Publicado: (2019)

Environmental control of Pub1 (NEDD4 family E3 ligase) in Schizosaccharomyces pombe is regulated by TORC2 and Gsk3
por: Wang, Tingting, et al.
Publicado: (2022)

Deprivation of the Periplasmic Chaperone SurA Reduces Virulence and Restores Antibiotic Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa
por: Klein, Kristina, et al.
Publicado: (2019)

Sophoricoside ameliorates cardiac hypertrophy by activating AMPK/mTORC1-mediated autophagy
por: Gao, Maomao, et al.
Publicado: (2020)

Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation
por: Caligaris, Marco, et al.
Publicado: (2023)

Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells
por: Khozooei, Shayan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_70tk418nsr3ovjuv3dpaku3nre