C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function

BACKGROUND: Acute myocardial infarction (MI) elicits an inflammatory response that drives tissue repair and adverse cardiac remodeling. Inflammatory cell trafficking after MI is controlled by C-X-C motif chemokine ligand 12 (CXCL12) and its receptor, C-X-C motif chemokine receptor 4 (CXCR4). CXCR4 a...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Dembowsky, Klaus, Chevalier, Eric, Stüve, Philipp, Korf-Klingebiel, Mortimer, Lochner, Matthias, Napp, L. Christian, Frank, Heike, Brinkmann, Eva, Kanwischer, Anna, Bauersachs, Johann, Gyöngyösi, Mariann, Sparwasser, Tim, Wollert, Kai C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467561/
https://www.ncbi.nlm.nih.gov/pubmed/30696265
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467561/
https://www.ncbi.nlm.nih.gov/pubmed/30696265
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036053

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