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C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function

BACKGROUND: Acute myocardial infarction (MI) elicits an inflammatory response that drives tissue repair and adverse cardiac remodeling. Inflammatory cell trafficking after MI is controlled by C-X-C motif chemokine ligand 12 (CXCL12) and its receptor, C-X-C motif chemokine receptor 4 (CXCR4). CXCR4 a...

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Detalles Bibliográficos
Autores principales:	Wang, Yong, Dembowsky, Klaus, Chevalier, Eric, Stüve, Philipp, Korf-Klingebiel, Mortimer, Lochner, Matthias, Napp, L. Christian, Frank, Heike, Brinkmann, Eva, Kanwischer, Anna, Bauersachs, Johann, Gyöngyösi, Mariann, Sparwasser, Tim, Wollert, Kai C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467561/ https://www.ncbi.nlm.nih.gov/pubmed/30696265 http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036053

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