Cargando…
Associations between sounds and actions in early auditory cortex of nonhuman primates
An individual may need to take different actions to the same stimulus in different situations to achieve a given goal. The selection of the appropriate action hinges on the previously learned associations between stimuli, actions, and outcomes in the situations. Here, using a go/no-go paradigm and a...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467566/ https://www.ncbi.nlm.nih.gov/pubmed/30946010 http://dx.doi.org/10.7554/eLife.43281 |
_version_ | 1783411287696343040 |
---|---|
author | Huang, Ying Heil, Peter Brosch, Michael |
author_facet | Huang, Ying Heil, Peter Brosch, Michael |
author_sort | Huang, Ying |
collection | PubMed |
description | An individual may need to take different actions to the same stimulus in different situations to achieve a given goal. The selection of the appropriate action hinges on the previously learned associations between stimuli, actions, and outcomes in the situations. Here, using a go/no-go paradigm and a symmetrical reward, we show that early auditory cortex of nonhuman primates represents such associations, in both the spiking activity and the local field potentials. Sound-evoked neuronal responses changed with sensorimotor associations shortly after sound onset, and the neuronal responses were largest when the sound signaled that a no-go response was required in a trial to obtain a reward. Our findings suggest that association processes take place in the auditory system and do not necessarily rely on association cortex. Thus, auditory cortex may contribute to a rapid selection of the appropriate motor responses to sounds during goal-directed behavior. |
format | Online Article Text |
id | pubmed-6467566 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-64675662019-04-17 Associations between sounds and actions in early auditory cortex of nonhuman primates Huang, Ying Heil, Peter Brosch, Michael eLife Neuroscience An individual may need to take different actions to the same stimulus in different situations to achieve a given goal. The selection of the appropriate action hinges on the previously learned associations between stimuli, actions, and outcomes in the situations. Here, using a go/no-go paradigm and a symmetrical reward, we show that early auditory cortex of nonhuman primates represents such associations, in both the spiking activity and the local field potentials. Sound-evoked neuronal responses changed with sensorimotor associations shortly after sound onset, and the neuronal responses were largest when the sound signaled that a no-go response was required in a trial to obtain a reward. Our findings suggest that association processes take place in the auditory system and do not necessarily rely on association cortex. Thus, auditory cortex may contribute to a rapid selection of the appropriate motor responses to sounds during goal-directed behavior. eLife Sciences Publications, Ltd 2019-04-04 /pmc/articles/PMC6467566/ /pubmed/30946010 http://dx.doi.org/10.7554/eLife.43281 Text en © 2019, Huang et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Huang, Ying Heil, Peter Brosch, Michael Associations between sounds and actions in early auditory cortex of nonhuman primates |
title | Associations between sounds and actions in early auditory cortex of nonhuman primates |
title_full | Associations between sounds and actions in early auditory cortex of nonhuman primates |
title_fullStr | Associations between sounds and actions in early auditory cortex of nonhuman primates |
title_full_unstemmed | Associations between sounds and actions in early auditory cortex of nonhuman primates |
title_short | Associations between sounds and actions in early auditory cortex of nonhuman primates |
title_sort | associations between sounds and actions in early auditory cortex of nonhuman primates |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467566/ https://www.ncbi.nlm.nih.gov/pubmed/30946010 http://dx.doi.org/10.7554/eLife.43281 |
work_keys_str_mv | AT huangying associationsbetweensoundsandactionsinearlyauditorycortexofnonhumanprimates AT heilpeter associationsbetweensoundsandactionsinearlyauditorycortexofnonhumanprimates AT broschmichael associationsbetweensoundsandactionsinearlyauditorycortexofnonhumanprimates |