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The distribution of T‐cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia

BACKGROUND: Phenotypic characterization of immune cells in the bone marrow (BM) of patients with acute myeloid leukemia (AML) is lacking. METHODS: T‐cell infiltration was quantified on BM biopsies from 13 patients with AML, and flow cytometry was performed on BM aspirates (BMAs) from 107 patients wi...

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Detalles Bibliográficos
Autores principales: Williams, Patrick, Basu, Sreyashi, Garcia‐Manero, Guillermo, Hourigan, Christopher S., Oetjen, Karolyn A., Cortes, Jorge E., Ravandi, Farhad, Jabbour, Elias J., Al‐Hamal, Zainab, Konopleva, Marina, Ning, Jing, Xiao, Lianchun, Hidalgo Lopez, Juliana, Kornblau, Steve M., Andreeff, Michael, Flores, Wilmer, Bueso‐Ramos, Carlos, Blando, Jorge, Galera, Pallavi, Calvo, Katherine R., Al‐Atrash, Gheath, Allison, James P., Kantarjian, Hagop M., Sharma, Padmanee, Daver, Naval G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467779/
https://www.ncbi.nlm.nih.gov/pubmed/30500073
http://dx.doi.org/10.1002/cncr.31896