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Ectopic Dpp signaling promotes stem cell competition through EGFR signaling in the Drosophila testis

Stem cell competition could select the fittest stem cells and potentially control tumorigenesis. However, little is known about the underlying molecular mechanisms. Here, we find that ectopic Decapentaplegic (Dpp) signal activation by expressing a constitutively active form of Thickveins (Tkv(CA)) i...

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Detalles Bibliográficos
Autores principales: Lu, Yanfen, Yao, Yuncong, Li, Zhouhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467874/
https://www.ncbi.nlm.nih.gov/pubmed/30992503
http://dx.doi.org/10.1038/s41598-019-42630-y