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Maslinic acid alleviates ischemia/reperfusion-induced inflammation by downregulation of NFκB-mediated adhesion molecule expression
Ischemia/reperfusion (I/R)-induced inflammation is associated with enhanced leukocyte rolling, adhesion and transmigration within the microcirculation. These steps are mediated by hypoxia-triggered signaling pathways, which upregulate adhesion molecule expression on endothelial cells and pericytes....
Autores principales: | Ampofo, Emmanuel, Berg, Julian J., Menger, Michael D., Laschke, Matthias W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467883/ https://www.ncbi.nlm.nih.gov/pubmed/30992483 http://dx.doi.org/10.1038/s41598-019-42465-7 |
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