CXCL12-CXCR4 pathway activates brown adipocytes and induces insulin resistance in CXCR4-deficient mice under high-fat diet

Brown adipose tissue (BAT) plays a role in energy expenditure and is involved in nutrient metabolism. C-X-C chemokine ligand 12 (CXCL12)-CXCR4 pathway regulates the immune, nervous, and cardiovascular systems and affects the adipose tissue. Here, we investigated the role of this pathway as an activa...

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Detalles Bibliográficos
Autores principales: Kurita, Kenichi, Ishikawa, Ko, Takeda, Kenji, Fujimoto, Masanori, Ono, Hiraku, Kumagai, Jin, Inoue, Hiromi, Yokoh, Hidetaka, Yokote, Koutaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467900/
https://www.ncbi.nlm.nih.gov/pubmed/30992469
http://dx.doi.org/10.1038/s41598-019-42127-8

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