Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4(+) T Cells in Multiple Sclerosis

Immune responses to citrullinated peptides have been described in autoimmune diseases like rheumatoid arthritis (RA) and multiple sclerosis (MS). We investigated the post-translational modification (PTM), arginine to citrulline, in brain tissue of MS patients and controls (C) by proteomics and subse...

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Detalles Bibliográficos
Autores principales: Faigle, Wolfgang, Cruciani, Carolina, Wolski, Witold, Roschitzki, Bernd, Puthenparampil, Marco, Tomas-Ojer, Paula, Sellés-Moreno, Carla, Zeis, Thomas, Jelcic, Ivan, Schaeren-Wiemers, Nicole, Sospedra, Mireia, Martin, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467957/
https://www.ncbi.nlm.nih.gov/pubmed/31024521
http://dx.doi.org/10.3389/fimmu.2019.00540

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