Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection

The IL-7/IL-7R pathway is essential for lymphocyte development and disturbances in the pathway can lead to immune deficiency or T cell mediated destruction. Here, the effect of transient hyperexpression of IL-7 was investigated on immune regulation and allograft rejection under immunosuppression. An...

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Detalles Bibliográficos
Autores principales: Schreiber, Maria, Weigelt, Marc, Karasinsky, Anne, Anastassiadis, Konstantinos, Schallenberg, Sonja, Petzold, Cathleen, Bonifacio, Ezio, Kretschmer, Karsten, Hommel, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467976/
https://www.ncbi.nlm.nih.gov/pubmed/31024566
http://dx.doi.org/10.3389/fimmu.2019.00742

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