Cargando…

Loss-of-function of sox3 causes follicle development retardation and reduces fecundity in zebrafish

Folliculogenesis is essential for production of female gametes in vertebrates. However, the molecular mechanisms underlying follicle development, particularly apoptosis regulation in ovary, remain elusive. Here, we generated sox3 knockout zebrafish lines using CRISPR/Cas9. sox3 knockout led to folli...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Qiang, Li, Cong, Ying, Ruhong, Lin, Heming, Li, Jingqiu, Zhao, Yu, Cheng, Hanhua, Zhou, Rongjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468042/
https://www.ncbi.nlm.nih.gov/pubmed/30588557
http://dx.doi.org/10.1007/s13238-018-0603-y