Cargando…

Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury

BACKGROUND: Mitochondrial dynamics play a critical role in mitochondrial function. The mitofusin 2 (MFN2) gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion to maintain and operate the mitochondrial network. Moreover, MFN2 is essential for mitophagy. In Ang II-in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Wenjun, Ma, Zhuang, An, Dongqi, Liu, Zuheng, Cai, Wanqiang, Bai, Yujia, Zhan, Qiong, Lai, Wenyan, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468045/ https://www.ncbi.nlm.nih.gov/pubmed/31024347 http://dx.doi.org/10.3389/fphys.2019.00411

Ejemplares similares

N-terminal truncated peroxisome proliferator-activated receptor-γ coactivator-1α alleviates phenylephrine-induced mitochondrial dysfunction and decreases lipid droplet accumulation in neonatal rat cardiomyocytes
por: Liu, Zuheng, et al.
Publicado: (2018)

Matrine Protects Cardiomyocytes Against Hyperglycemic Stress by Promoting Mitofusin 2-Induced Mitochondrial Fusion
por: Xiao, Tong, et al.
Publicado: (2021)

A CRM1 Inhibitor Alleviates Cardiac Hypertrophy and Increases the Nuclear Distribution of NT-PGC-1α in NRVMs
por: Liu, Zuheng, et al.
Publicado: (2019)

Retraction: Matrine protects cardiomyocytes against hyperglycemic stress by promoting mitofusin 2-induced mitochondrial fusion
Publicado: (2022)

Metformin Increases Cardiac Rupture After Myocardial Infarction via the AMPK-MTOR/PGC-1α Signaling Pathway in Rats with Acute Myocardial Infarction
por: Hua, Jinghai, et al.
Publicado: (2018)

Role of Mitofusins and Mitophagy in Life or Death Decisions
por: Joaquim, Mariana, et al.
Publicado: (2020)

Mitochondrial Fission and Mitophagy Coordinately Restrict High Glucose Toxicity in Cardiomyocytes
por: Kobayashi, Satoru, et al.
Publicado: (2020)

Mitofusin 2 Dysfunction and Disease in Mice and Men
por: Dorn, Gerald W.
Publicado: (2020)

Moderate-Intensity Exercise Affects Gut Microbiome Composition and Influences Cardiac Function in Myocardial Infarction Mice
por: Liu, Zuheng, et al.
Publicado: (2017)

Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events
por: Li, Jiajia, et al.
Publicado: (2022)

Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice
por: An, Dongqi, et al.
Publicado: (2021)

Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes
por: Meng, Ting-ting, et al.
Publicado: (2021)

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
por: Tanaka, Atsushi, et al.
Publicado: (2010)

Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 Ligases
por: Escobar-Henriques, Mafalda, et al.
Publicado: (2019)

Mitofusin-2 Enhances Mitochondrial Contact With the Endoplasmic Reticulum and Promotes Diabetic Cardiomyopathy
por: Zhang, Jing, et al.
Publicado: (2021)

Retraction: Mitofusin-2 enhances mitochondrial contact with the endoplasmic reticulum and promotes diabetic cardiomyopathy
Publicado: (2022)

Mitofusin 2 Is Essential for IP(3)-Mediated SR/Mitochondria Metabolic Feedback in Ventricular Myocytes
por: Seidlmayer, Lea K., et al.
Publicado: (2019)

Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides
por: Thai, Phung N., et al.
Publicado: (2019)

Mitochondrial fusion: Reaching the end of mitofusin’s tether
por: Formosa, Luke E., et al.
Publicado: (2016)

Back to The Fusion: Mitofusin-2 in Alzheimer’s Disease
por: Sita, Giulia, et al.
Publicado: (2020)

Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function
por: Ma, Zhuang, et al.
Publicado: (2023)

Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins
por: Yu, Chia-Yi, et al.
Publicado: (2015)

Recent insights into the structure and function of Mitofusins in mitochondrial fusion
por: Cohen, Mickael M, et al.
Publicado: (2018)

Berberine Promotes Cardiac Function by Upregulating PINK1/Parkin-Mediated Mitophagy in Heart Failure
por: Abudureyimu, Miyesaier, et al.
Publicado: (2020)

Common Traits Spark the Mitophagy/Xenophagy Interplay
por: Singh, Aarti, et al.
Publicado: (2018)

Association between admission plasma 2-oxoglutarate levels and short-term outcomes in patients with acute heart failure: a prospective cohort study
por: Peng, Zhengliang, et al.
Publicado: (2019)

Association of Urine Albumin/Creatinine Ratio below 30 mg/g and Left Ventricular Hypertrophy in Patients with Type 2 Diabetes
por: Xie, Xiangkun, et al.
Publicado: (2020)

Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy
por: Sureshbabu, Angara, et al.
Publicado: (2013)

Mechanisms and Functions of Mitophagy and Potential Roles in Renal Disease
por: Zuo, Zhenying, et al.
Publicado: (2020)

Editorial: Autophagy and Mitophagy in Skeletal Muscle Health and Disease
por: Hussain, Sabah N. A., et al.
Publicado: (2021)

Mitophagy: A potential therapeutic target for insulin resistance
por: Ning, Peng, et al.
Publicado: (2022)

The molecular mechanisms and intervention strategies of mitophagy in cardiorenal syndrome
por: Yao, Mengying, et al.
Publicado: (2022)

Calcium Spark Detection and Event-Based Classification of Single Cardiomyocyte Using Deep Learning
por: Yang, Shengqi, et al.
Publicado: (2021)

Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset
por: Li, Yu-Jie, et al.
Publicado: (2019)

Communication Between Cardiomyocytes and Fibroblasts During Cardiac Ischemia/Reperfusion and Remodeling: Roles of TGF-β, CTGF, the Renin Angiotensin Axis, and Non-coding RNA Molecules
por: Flores-Vergara, Raúl, et al.
Publicado: (2021)

Pro-diversity mitofusins
por: LeBrasseur, Nicole
Publicado: (2007)

The INs and OUTs of mitofusins
por: Giacomello, Marta, et al.
Publicado: (2018)

Molecular Perspectives of Mitophagy in Myocardial Stress: Pathophysiology and Therapeutic Targets
por: Ji, Haizhe, et al.
Publicado: (2021)

The Emerging Role of FUNDC1-Mediated Mitophagy in Cardiovascular Diseases
por: Liu, Lei, et al.
Publicado: (2021)

Mitochondrial Dynamics: Biogenesis, Fission, Fusion, and Mitophagy in the Regulation of Stem Cell Behaviors
por: Fu, Wenyan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_flg6jv37ctgncgjmtclmar7cih