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Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells
In the CNS, oligodendrocytes are responsible for myelin formation and maintenance. Following spinal cord injury, oligodendrocyte loss and an inhibitory milieu compromise remyelination and recovery. Here, we explored the role of retinoic acid receptor-beta (RARβ) signaling in remyelination. Using a m...
Autores principales: | Goncalves, Maria B., Wu, Yue, Clarke, Earl, Grist, John, Hobbs, Carl, Trigo, Diogo, Jack, Julian, Corcoran, Jonathan P.T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468108/ https://www.ncbi.nlm.nih.gov/pubmed/30760627 http://dx.doi.org/10.1523/JNEUROSCI.2922-18.2019 |
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