Oncolytic Herpes Simplex Virus and PI3K Inhibitor BKM120 Synergize to Promote Killing of Prostate Cancer Stem-like Cells

Novel therapies to override chemo-radiation resistance in prostate cancer (PCa) are needed. Prostate cancer sphere-forming cells (PCSCs) (also termed prostate cancer stem-like cells) likely participate in tumor progression and recurrence, and they are important therapeutic targets. We established PC...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Ning, Jianfang, Wakimoto, Hiroaki, Wu, Shulin, Wu, Chin-lee, Humphrey, Melissa R., Rabkin, Samuel D., Martuza, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468160/
https://www.ncbi.nlm.nih.gov/pubmed/31016228
http://dx.doi.org/10.1016/j.omto.2019.03.008

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