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Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast

Oxidative DNA damage is a threat to genome stability. Using a genetic system in yeast that allows detection of mitotic recombination, we found that the frequency of crossovers is greatly elevated when cells are treated with hydrogen peroxide (H(2)O(2)). Using a combination of microarray analysis and...

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Detalles Bibliográficos
Autores principales:	Zhang, Ke, Zheng, Dao-Qiong, Sui, Yang, Qi, Lei, Petes, Thomas D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468167/ https://www.ncbi.nlm.nih.gov/pubmed/30668788 http://dx.doi.org/10.1093/nar/gkz027

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