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Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 Axis
BACKGROUND & AIMS: Intratumor heterogeneity is a common feature of colorectal cancer (CRC). Here, we analyzed whether mesenchymal-like CRC cells promote the progression of epithelial-like CRC cells via paracrine mechanisms. METHODS: Six CRC cell lines that show an epithelial phenotype were treat...
Autores principales: | Rokavec, Matjaz, Bouznad, Nassim, Hermeking, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468198/ https://www.ncbi.nlm.nih.gov/pubmed/30831320 http://dx.doi.org/10.1016/j.jcmgh.2019.02.003 |
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