TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment

The telomeric protein TRF2 is overexpressed in several human malignancies and contributes to tumorigenesis even though the molecular mechanism is not completely understood. By using a high-throughput approach based on the multiplexed Luminex X-MAP technology, we demonstrated that TRF2 dramatically a...

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Detalles Bibliográficos
Autores principales: Zizza, Pasquale, Dinami, Roberto, Porru, Manuela, Cingolani, Chiara, Salvati, Erica, Rizzo, Angela, D’Angelo, Carmen, Petti, Eleonora, Amoreo, Carla Azzurra, Mottolese, Marcella, Sperduti, Isabella, Chambery, Angela, Russo, Rosita, Ostano, Paola, Chiorino, Giovanna, Blandino, Giovanni, Sacconi, Andrea, Cherfils-Vicini, Julien, Leonetti, Carlo, Gilson, Eric, Biroccio, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468246/
https://www.ncbi.nlm.nih.gov/pubmed/30698737
http://dx.doi.org/10.1093/nar/gkz041

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