circ-Sirt1 controls NF-κB activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to miR-132/212 in vascular smooth muscle cells

NF-κB-mediated inflammatory phenotypic switching of vascular smooth muscle cells (VSMCs) plays a central role in atherosclerosis and neointimal formation. However, little is known about the roles of circRNAs in the regulation of NF-κB signaling. Here, we identify the involvement of circ-Sirt1 that w...

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Detalles Bibliográficos
Autores principales: Kong, Peng, Yu, Yuan, Wang, Lu, Dou, Yong-Qing, Zhang, Xu-Hui, Cui, Yan, Wang, Hai-Yue, Yong, Yu-Tao, Liu, Ya-Bin, Hu, Hai-Juan, Cui, Wei, Sun, Shao-Guang, Li, Bing-Hui, Zhang, Fan, Han, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468289/
https://www.ncbi.nlm.nih.gov/pubmed/30820544
http://dx.doi.org/10.1093/nar/gkz141

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