Nucleus‐Targeted Organoiridium–Albumin Conjugate for Photodynamic Cancer Therapy

An organoiridium–albumin bioconjugate (Ir1‐HSA) was synthesized by reaction of a pendant maleimide ligand with human serum albumin. The phosphorescence of Ir1‐HSA was enhanced significantly compared to parent complex Ir1. The long phosphorescence lifetime and high (1)O(2) quantum yield of Ir1‐HSA ar...

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Detalles Bibliográficos
Autores principales: Zhang, Pingyu, Huang, Huaiyi, Banerjee, Samya, Clarkson, Guy J., Ge, Chen, Imberti, Cinzia, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468315/
https://www.ncbi.nlm.nih.gov/pubmed/30552796
http://dx.doi.org/10.1002/anie.201813002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468315/
https://www.ncbi.nlm.nih.gov/pubmed/30552796
http://dx.doi.org/10.1002/anie.201813002

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