Cargando…

Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group

The management of older cancer patients remains difficult because of data paucity. Radiation oncologists need to identify potential issues which could affect treatment of those patients. A workshop was organized in Barcelona among international radiation oncologists with special interest in the mana...

Descripción completa

Detalles Bibliográficos
Autores principales: Popescu, Tiberiu, Karlsson, Ulf, Vinh-Hung, Vincent, Trigo, Lurdes, Thariat, Juliette, Vuong, Te, Baumert, Brigitta G., Motta, Micaela, Zamagni, Alice, Bonet, Marta, Myint, Arthur Sun, Lara, Pedro Carlos, Nguyen, Nam P., Arenas, Meritxell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468336/
https://www.ncbi.nlm.nih.gov/pubmed/30884827
http://dx.doi.org/10.3390/cancers11030371
_version_ 1783411410757222400
author Popescu, Tiberiu
Karlsson, Ulf
Vinh-Hung, Vincent
Trigo, Lurdes
Thariat, Juliette
Vuong, Te
Baumert, Brigitta G.
Motta, Micaela
Zamagni, Alice
Bonet, Marta
Myint, Arthur Sun
Lara, Pedro Carlos
Nguyen, Nam P.
Arenas, Meritxell
author_facet Popescu, Tiberiu
Karlsson, Ulf
Vinh-Hung, Vincent
Trigo, Lurdes
Thariat, Juliette
Vuong, Te
Baumert, Brigitta G.
Motta, Micaela
Zamagni, Alice
Bonet, Marta
Myint, Arthur Sun
Lara, Pedro Carlos
Nguyen, Nam P.
Arenas, Meritxell
author_sort Popescu, Tiberiu
collection PubMed
description The management of older cancer patients remains difficult because of data paucity. Radiation oncologists need to identify potential issues which could affect treatment of those patients. A workshop was organized in Barcelona among international radiation oncologists with special interest in the management of older cancer patients on April 22, 2018. The following consensus was reached: 1. Older cancer patients often faced unconscious discriminating bias from cancer specialists and institutions because of their chronological age. 2. Advances in radiotherapy techniques have allowed patients with multiple co-morbidities precluding surgery or systemic therapy to achieve potential cure in early disease stages. 3. The lack of biomarkers for frailty remains an impediment to future research. 4. Access to healthcare insurance and daily transportation remains an issue in many countries; 5. Hypofractionation, brachytherapy, or stereotactic techniques may be ideally suited for older cancer patients to minimize transportation issues and to improve tolerance to radiotherapy. 6. Patients with locally advanced disease who are mentally and physically fit should receive combined therapy for potential cure. 7. The role of systemic therapy alone or combined with radiotherapy for frail patients needs to be defined in future clinical trials because of targeted agents or immunotherapy may be less toxic compared to conventional chemotherapy.
format Online
Article
Text
id pubmed-6468336
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-64683362019-04-24 Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group Popescu, Tiberiu Karlsson, Ulf Vinh-Hung, Vincent Trigo, Lurdes Thariat, Juliette Vuong, Te Baumert, Brigitta G. Motta, Micaela Zamagni, Alice Bonet, Marta Myint, Arthur Sun Lara, Pedro Carlos Nguyen, Nam P. Arenas, Meritxell Cancers (Basel) Perspective The management of older cancer patients remains difficult because of data paucity. Radiation oncologists need to identify potential issues which could affect treatment of those patients. A workshop was organized in Barcelona among international radiation oncologists with special interest in the management of older cancer patients on April 22, 2018. The following consensus was reached: 1. Older cancer patients often faced unconscious discriminating bias from cancer specialists and institutions because of their chronological age. 2. Advances in radiotherapy techniques have allowed patients with multiple co-morbidities precluding surgery or systemic therapy to achieve potential cure in early disease stages. 3. The lack of biomarkers for frailty remains an impediment to future research. 4. Access to healthcare insurance and daily transportation remains an issue in many countries; 5. Hypofractionation, brachytherapy, or stereotactic techniques may be ideally suited for older cancer patients to minimize transportation issues and to improve tolerance to radiotherapy. 6. Patients with locally advanced disease who are mentally and physically fit should receive combined therapy for potential cure. 7. The role of systemic therapy alone or combined with radiotherapy for frail patients needs to be defined in future clinical trials because of targeted agents or immunotherapy may be less toxic compared to conventional chemotherapy. MDPI 2019-03-16 /pmc/articles/PMC6468336/ /pubmed/30884827 http://dx.doi.org/10.3390/cancers11030371 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Popescu, Tiberiu
Karlsson, Ulf
Vinh-Hung, Vincent
Trigo, Lurdes
Thariat, Juliette
Vuong, Te
Baumert, Brigitta G.
Motta, Micaela
Zamagni, Alice
Bonet, Marta
Myint, Arthur Sun
Lara, Pedro Carlos
Nguyen, Nam P.
Arenas, Meritxell
Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group
title Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group
title_full Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group
title_fullStr Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group
title_full_unstemmed Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group
title_short Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group
title_sort challenges facing radiation oncologists in the management of older cancer patients: consensus of the international geriatric radiotherapy group
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468336/
https://www.ncbi.nlm.nih.gov/pubmed/30884827
http://dx.doi.org/10.3390/cancers11030371
work_keys_str_mv AT popescutiberiu challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT karlssonulf challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT vinhhungvincent challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT trigolurdes challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT thariatjuliette challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT vuongte challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT baumertbrigittag challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT mottamicaela challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT zamagnialice challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT bonetmarta challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT myintarthursun challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT larapedrocarlos challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT nguyennamp challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup
AT arenasmeritxell challengesfacingradiationoncologistsinthemanagementofoldercancerpatientsconsensusoftheinternationalgeriatricradiotherapygroup