Tailoring Ovarian Cancer Treatment: Implications of BRCA1/2 Mutations

High grade serous ovarian cancer (HGSOC) is the most common epithelial ovarian cancer, harbouring more than 20% germline or somatic mutations in the tumour suppressor genes BRCA1 and BRCA2. These genes are involved in both DNA damage repair process via homologous recombination (HR) and transcription...

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Detalles Bibliográficos
Autores principales: Madariaga, Ainhoa, Lheureux, Stephanie, Oza, Amit M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468364/
https://www.ncbi.nlm.nih.gov/pubmed/30909618
http://dx.doi.org/10.3390/cancers11030416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468364/
https://www.ncbi.nlm.nih.gov/pubmed/30909618
http://dx.doi.org/10.3390/cancers11030416

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