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Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines

Clear cell renal cell carcinoma (ccRCC) is the most common and lethal form of urological cancer diagnosed globally. Mutations of the von Hippel-Lindau (VHL) tumor-suppressor gene and the resultant overexpression of hypoxia-inducible factor (HIF)-1α protein are considered hallmarks of ccRCC. Persiste...

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Detalles Bibliográficos
Autores principales: Pasha, Mazhar, Sivaraman, Siveen K., Frantz, Ronald, Agouni, Abdelali, Munusamy, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468376/
https://www.ncbi.nlm.nih.gov/pubmed/30909494
http://dx.doi.org/10.3390/biom9030113