Cargando…

Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery

The natural polyphenol Resveratrol (RSV) claims numerous positive effects on health due to the well documented biological effects demonstrating its potential as a disease-preventing agent and as adjuvant for treatment of a wide variety of chronic diseases. Since several studies, both in vitro and in...

Descripción completa

Detalles Bibliográficos
Autores principales: Murgia, Denise, Mauceri, Rodolfo, Campisi, Giuseppina, De Caro, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468380/
https://www.ncbi.nlm.nih.gov/pubmed/30857241
http://dx.doi.org/10.3390/biom9030094
_version_ 1783411421012295680
author Murgia, Denise
Mauceri, Rodolfo
Campisi, Giuseppina
De Caro, Viviana
author_facet Murgia, Denise
Mauceri, Rodolfo
Campisi, Giuseppina
De Caro, Viviana
author_sort Murgia, Denise
collection PubMed
description The natural polyphenol Resveratrol (RSV) claims numerous positive effects on health due to the well documented biological effects demonstrating its potential as a disease-preventing agent and as adjuvant for treatment of a wide variety of chronic diseases. Since several studies, both in vitro and in vivo, have highlighted the protective bone aptitude of RSV both as promoter of osteoblasts’ proliferation and antagonist of osteoclasts’ differentiation, they could be interesting in view of applications in the field of dentistry and maxillofacial surgery. This review has brought together experimental findings on the use of RSV in the regeneration of bone tissue comprising also its application associated with scaffolds and non-transfusional hemocomponents.
format Online
Article
Text
id pubmed-6468380
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-64683802019-04-24 Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery Murgia, Denise Mauceri, Rodolfo Campisi, Giuseppina De Caro, Viviana Biomolecules Review The natural polyphenol Resveratrol (RSV) claims numerous positive effects on health due to the well documented biological effects demonstrating its potential as a disease-preventing agent and as adjuvant for treatment of a wide variety of chronic diseases. Since several studies, both in vitro and in vivo, have highlighted the protective bone aptitude of RSV both as promoter of osteoblasts’ proliferation and antagonist of osteoclasts’ differentiation, they could be interesting in view of applications in the field of dentistry and maxillofacial surgery. This review has brought together experimental findings on the use of RSV in the regeneration of bone tissue comprising also its application associated with scaffolds and non-transfusional hemocomponents. MDPI 2019-03-08 /pmc/articles/PMC6468380/ /pubmed/30857241 http://dx.doi.org/10.3390/biom9030094 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Murgia, Denise
Mauceri, Rodolfo
Campisi, Giuseppina
De Caro, Viviana
Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery
title Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery
title_full Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery
title_fullStr Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery
title_full_unstemmed Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery
title_short Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery
title_sort advance on resveratrol application in bone regeneration: progress and perspectives for use in oral and maxillofacial surgery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468380/
https://www.ncbi.nlm.nih.gov/pubmed/30857241
http://dx.doi.org/10.3390/biom9030094
work_keys_str_mv AT murgiadenise advanceonresveratrolapplicationinboneregenerationprogressandperspectivesforuseinoralandmaxillofacialsurgery
AT maucerirodolfo advanceonresveratrolapplicationinboneregenerationprogressandperspectivesforuseinoralandmaxillofacialsurgery
AT campisigiuseppina advanceonresveratrolapplicationinboneregenerationprogressandperspectivesforuseinoralandmaxillofacialsurgery
AT decaroviviana advanceonresveratrolapplicationinboneregenerationprogressandperspectivesforuseinoralandmaxillofacialsurgery