Cargando…

[Pt(O,O′-acac)(γ-acac)(DMS)] Induces Autophagy in Caki-1 Renal Cancer Cells

We have demonstrated the cytotoxic effects of [Pt(O,O′-acac)(γ-acac)(dimethyl sulfide (DMS))] on various immortalized cell lines, in primary cultures, and in murine xenograft models in vivo. Recently, we also showed that [Pt(O,O′-acac)(γ-acac)(DMS)] is able to kill Caki-1 renal cells both in vivo an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Antonaci, Giovanna, Cossa, Luca Giulio, Muscella, Antonella, Vetrugno, Carla, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468382/ https://www.ncbi.nlm.nih.gov/pubmed/30845773 http://dx.doi.org/10.3390/biom9030092

Ejemplares similares

In Vitro and In Vivo Antitumor Activity of [Pt(O,O′-acac)(γ-acac)(DMS)] in Malignant Pleural Mesothelioma
por: Muscella, Antonella, et al.
Publicado: (2016)

Apoptosis by [Pt(O,O′-acac)(γ-acac)(DMS)] requires PKC-δ mediated p53 activation in malignant pleural mesothelioma
por: Muscella, Antonella, et al.
Publicado: (2017)

Correction: Apoptosis by [Pt(O,O′-acac)(γ-acac)(DMS)] requires PKC-δ mediated p53 activation in malignant pleural mesothelioma
por: Muscella, Antonella, et al.
Publicado: (2018)

Antitumor activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in mouse xenograft model of breast cancer
por: Muscella, A, et al.
Publicado: (2014)

Response of Cisplatin Resistant Skov-3 Cells to [Pt(O,O′-Acac)(γ-Acac)(DMS)] Treatment Revealed by a Metabolomic (1)H-NMR Study
por: De Castro, Federica, et al.
Publicado: (2018)

[Pt(O,O’-acac)(γ-acac)(DMS)] Alters SH-SY5Y Cell Migration and Invasion by the Inhibition of Na(+)/H(+) Exchanger Isoform 1 Occurring through a PKC-ε/ERK/mTOR Pathway
por: Muscella, Antonella, et al.
Publicado: (2014)

Correction: [Pt(O,O'-acac)(γ-acac)(DMS)] Alters SH-SY5Y Cell Migration and Invasion by the Inhibition of Na(+)/H(+) Exchanger Isoform 1 Occurring through a PKC-ε/ERK/mTOR Pathway
Publicado: (2015)

Toward Detection of the Molecular Parity Violation in Chiral Ru(acac)(3) and Os(acac)(3)
por: Fiechter, Marit R., et al.
Publicado: (2022)

A Fast Transient Absorption Study of Co(AcAc)(3)
por: Ferrari, Luisa, et al.
Publicado: (2019)

Adsorption and Dissociation of Ni(acac)(2) on Iron by Ab Initio Calculations
por: Corsini, Chiara, et al.
Publicado: (2020)

Racemization Pathway for MoO(2)(acac)(2) Favored over Ray–Dutt, Bailar, and Conte–Hippler Twists
por: Dhimba, George, et al.
Publicado: (2022)

Electrospinning Preparation, Structure, and Properties of Fe(3)O(4)/Tb(acac)(3)phen/Polystyrene Bifunctional Microfibers
por: Liu, Lina, et al.
Publicado: (2023)

Synthesis of Polyacids by Copolymerization of L-Lactide with MTC-COOH Using Zn[(acac)(L)H(2)O] Complex as an Initiator
por: Jaworska, Joanna, et al.
Publicado: (2022)

Homo- and Heteropolymetallic Complexes of the Hybrid, Ambidentate N-Heterocyclic Carbene Ligand IMes-acac
por: César, Vincent, et al.
Publicado: (2018)

A new platinum(II) compound anticancer drug candidate with selective cytotoxicity for breast cancer cells
por: Muscella, A, et al.
Publicado: (2013)

A new platinum(II) compound anticancer drug candidate with selective cytotoxicity for breast cancer cells
por: Muscella, A, et al.
Publicado: (2014)

Immunolocalization of the AT-1R Ang II Receptor in Human Kidney Cancer
por: Muscella, Antonella, et al.
Publicado: (2023)

Temperature Dependence of Spin–Phonon Coupling in [VO(acac)(2)]: A Computational and Spectroscopic Study
por: Albino, Andrea, et al.
Publicado: (2021)

Tuning Emission Lifetimes of Ir(C^N)(2)(acac) Complexes with Oligo(phenyleneethynylene) Groups
por: Davidson, Ross, et al.
Publicado: (2023)

SiO(2)-PVA-Fe(acac)(3) Hybrid Based Superparamagnetic Nanocomposites for Nanomedicine: Morpho-textural Evaluation and In Vitro Cytotoxicity Assay
por: Putz, Ana-Maria, et al.
Publicado: (2020)

The first oxazoline adduct of Zn(acac)(2): bis(acetylacetonato-κ(2) O,O′)(2-phenyl-2-oxazoline-κN)zinc(II)
por: del Río, Ignacio, et al.
Publicado: (2008)

Syntheses and crystal structures of three [M(acac)(2)(TMEDA)] complexes (M = Mn, Fe and Zn)
por: Halz, Jan Henrik, et al.
Publicado: (2020)

Preparation and Characterization of AMT/Co(acac)(3)-Loaded PAN/PS Micro-Nanofibers with Large through-Pores
por: Wang, Fei-Fei, et al.
Publicado: (2019)

Evaluation of the Antitumor Effects of Platinum-Based [Pt(η(1)-C(2)H(4)-OR)(DMSO)(phen)](+) (R = Me, Et) Cationic Organometallic Complexes on Chemoresistant Pancreatic Cancer Cell Lines
por: Stefàno, Erika, et al.
Publicado: (2023)

acACS: Improving the Prediction Accuracy of Protein Subcellular Locations and Protein Classification by Incorporating the Average Chemical Shifts Composition
por: Fan, Guo-Liang, et al.
Publicado: (2014)

Sustainable oxidation of cyclohexane catalyzed by a VO(acac)(2)-oxalic acid tandem: the electrochemical motive of the process efficiency
por: Pokutsa, Alexander, et al.
Publicado: (2020)

Synthesis of the Bacteriostatic Poly(l-Lactide) by Using Zinc (II)[(acac)(L)H(2)O] (L = Aminoacid-Based Chelate Ligands) as an Effective ROP Initiator
por: Barczyńska-Felusiak, Renata, et al.
Publicado: (2021)

Comparative Evaluation of Cu(acac)(2) and {[Cu(μ-O,O′-NO(3)) (L-arg) (2,2′-bpy)]·NO(3)}(n) as Potential Precursors of Electroless Metallization of Laser-Activated Polymer Materials
por: Jagodziński, Bartłomiej, et al.
Publicado: (2021)

A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η(1)-C(2)H(4)OMe)(DMSO)(phen)](+) (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells
por: De Castro, Federica, et al.
Publicado: (2022)

(R,R)-BD-AcAc2 Mitigates Chronic Colitis in Rats: A Promising Multi-Pronged Approach Modulating Inflammasome Activity, Autophagy, and Pyroptosis
por: Saber, Sameh, et al.
Publicado: (2023)

Synthesis and Evaluation of the Cytotoxic Activity of Water-Soluble Cationic Organometallic Complexes of the Type [Pt(η(1)-C(2)H(4)OMe)(L)(Phen)](+) (L = NH(3), DMSO; Phen = 1,10-Phenanthroline)
por: De Castro, Federica, et al.
Publicado: (2021)

Magneto-Induced Hyperthermia and Temperature Detection in Single Iron Oxide Core-Silica/Tb(3+)/Eu(3+)(Acac) Shell Nano-Objects
por: Nigoghossian, Karina, et al.
Publicado: (2022)

Novel Poly(L-lactide-co-ε-caprolactone) Matrices Obtained with the Use of Zr[Acac](4) as Nontoxic Initiator for Long-Term Release of Immunosuppressive Drugs
por: Jelonek, Katarzyna, et al.
Publicado: (2013)

Comparative study of post-growth annealing of Cu(hfac)(2), Co(2)(CO)(8) and Me(2)Au(acac) metal precursors deposited by FEBID
por: Puydinger dos Santos, Marcos Vinicius, et al.
Publicado: (2018)

The effects of training on hormonal concentrations and physical performance of football referees
por: Muscella, Antonella, et al.
Publicado: (2021)

Identification of Genetic Polymorphisms of PI, PIII, and Exon 53 in the Acetyl-CoA Carboxylase-α (ACACα) Gene and Their Association with Milk Composition Traits of Najdi Sheep
por: Matar, Abdulkareem M., et al.
Publicado: (2023)

Effects on Children’s Physical and Mental Well-Being of a Physical-Activity-Based School Intervention Program: A Randomized Study
por: Marsigliante, Santo, et al.
Publicado: (2023)

One-pot synthesis for gradient copolymers via concurrent tandem living radical polymerization: mild and selective transesterification of methyl acrylate through Al(acac)(3) with common alcohols
por: Huynh, Tam Thi-Thanh, et al.
Publicado: (2021)

Mutagenic Tests Confirm That New Acetylacetonate Pt(II) Complexes Induce Apoptosis in Cancer Cells Interacting with Nongenomic Biological Targets
por: De Pascali, Sandra Angelica, et al.
Publicado: (2011)

The Regulation of Fat Metabolism during Aerobic Exercise
por: Muscella, Antonella, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jb847qvshsggo6k3tdeagj0vcc