Graphene Oxide-Based Targeting of Extracellular Cathepsin D and Cathepsin L As A Novel Anti-Metastatic Enzyme Cancer Therapy

Overexpression and secretion of the enzymes cathepsin D (CathD) and cathepsin L (CathL) is associated with metastasis in several human cancers. As a superfamily, extracellularly, these proteins may act within the tumor microenvironment to drive cancer progression, proliferation, invasion and metasta...

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Detalles Bibliográficos
Autores principales: Tabish, Tanveer A., Pranjol, Md Zahidul I., Horsell, David W., Rahat, Alma A. M., Whatmore, Jacqueline L., Winyard, Paul G., Zhang, Shaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468385/
https://www.ncbi.nlm.nih.gov/pubmed/30845739
http://dx.doi.org/10.3390/cancers11030319

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