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Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients

Depression is a mental disorder characterized by recurrent sadness and loss of interest in the enjoyment of the positive aspects of life, in addition to fatigue, causing inability to perform daily activities, which leads to a loss of quality of life. To monitor depression (unipolar and bipolar patie...

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Autores principales: Zanella-Calzada, Laura A., Galván-Tejada, Carlos E., Chávez-Lamas, Nubia M., Gracia-Cortés, M. del Carmen, Magallanes-Quintanar, Rafael, Celaya-Padilla, José M., Galván-Tejada, Jorge I., Gamboa-Rosales, Hamurabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468429/
https://www.ncbi.nlm.nih.gov/pubmed/30634621
http://dx.doi.org/10.3390/diagnostics9010008
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author Zanella-Calzada, Laura A.
Galván-Tejada, Carlos E.
Chávez-Lamas, Nubia M.
Gracia-Cortés, M. del Carmen
Magallanes-Quintanar, Rafael
Celaya-Padilla, José M.
Galván-Tejada, Jorge I.
Gamboa-Rosales, Hamurabi
author_facet Zanella-Calzada, Laura A.
Galván-Tejada, Carlos E.
Chávez-Lamas, Nubia M.
Gracia-Cortés, M. del Carmen
Magallanes-Quintanar, Rafael
Celaya-Padilla, José M.
Galván-Tejada, Jorge I.
Gamboa-Rosales, Hamurabi
author_sort Zanella-Calzada, Laura A.
collection PubMed
description Depression is a mental disorder characterized by recurrent sadness and loss of interest in the enjoyment of the positive aspects of life, in addition to fatigue, causing inability to perform daily activities, which leads to a loss of quality of life. To monitor depression (unipolar and bipolar patients), traditional methods rely on reports from patients; nevertheless, bias is commonly present in them. To overcome this problem, Ecological Momentary Assessment (EMA) reports have been widely used, which include data of the behavior, feelings and other types of activities recorded almost in real time through the use of portable devices and smartphones containing motion sensors. In this work a methodology was proposed to detect depressive subjects from control subjects based in the data of their motor activity, recorded by a wearable device, obtained from the “Depresjon” database. From the motor activity signals, the extraction of statistical features was carried out to subsequently feed a random forest classifier. Results show a sensitivity value of 0.867, referring that those subjects with presence of depression have a degree of 86.7% of being correctly classified, while the specificity shows a value of 0.919, referring that those subjects with absence of depression have a degree of 91.9% of being classified with a correct response, using the motor activity signal provided from the wearable device. Based on these results, it is concluded that the motor activity allows distinguishing between the two classes, providing a preliminary and automated tool to specialists for the diagnosis of depression.
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spelling pubmed-64684292019-04-19 Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients Zanella-Calzada, Laura A. Galván-Tejada, Carlos E. Chávez-Lamas, Nubia M. Gracia-Cortés, M. del Carmen Magallanes-Quintanar, Rafael Celaya-Padilla, José M. Galván-Tejada, Jorge I. Gamboa-Rosales, Hamurabi Diagnostics (Basel) Article Depression is a mental disorder characterized by recurrent sadness and loss of interest in the enjoyment of the positive aspects of life, in addition to fatigue, causing inability to perform daily activities, which leads to a loss of quality of life. To monitor depression (unipolar and bipolar patients), traditional methods rely on reports from patients; nevertheless, bias is commonly present in them. To overcome this problem, Ecological Momentary Assessment (EMA) reports have been widely used, which include data of the behavior, feelings and other types of activities recorded almost in real time through the use of portable devices and smartphones containing motion sensors. In this work a methodology was proposed to detect depressive subjects from control subjects based in the data of their motor activity, recorded by a wearable device, obtained from the “Depresjon” database. From the motor activity signals, the extraction of statistical features was carried out to subsequently feed a random forest classifier. Results show a sensitivity value of 0.867, referring that those subjects with presence of depression have a degree of 86.7% of being correctly classified, while the specificity shows a value of 0.919, referring that those subjects with absence of depression have a degree of 91.9% of being classified with a correct response, using the motor activity signal provided from the wearable device. Based on these results, it is concluded that the motor activity allows distinguishing between the two classes, providing a preliminary and automated tool to specialists for the diagnosis of depression. MDPI 2019-01-10 /pmc/articles/PMC6468429/ /pubmed/30634621 http://dx.doi.org/10.3390/diagnostics9010008 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zanella-Calzada, Laura A.
Galván-Tejada, Carlos E.
Chávez-Lamas, Nubia M.
Gracia-Cortés, M. del Carmen
Magallanes-Quintanar, Rafael
Celaya-Padilla, José M.
Galván-Tejada, Jorge I.
Gamboa-Rosales, Hamurabi
Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients
title Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients
title_full Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients
title_fullStr Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients
title_full_unstemmed Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients
title_short Feature Extraction in Motor Activity Signal: Towards a Depression Episodes Detection in Unipolar and Bipolar Patients
title_sort feature extraction in motor activity signal: towards a depression episodes detection in unipolar and bipolar patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468429/
https://www.ncbi.nlm.nih.gov/pubmed/30634621
http://dx.doi.org/10.3390/diagnostics9010008
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