Cargando…
Conserved Glycines Control Disorder and Function in the Cold-Regulated Protein, COR15A
Cold-regulated (COR) 15A is an intrinsically disordered protein (IDP) from Arabidopsis thaliana important for freezing tolerance. During freezing-induced cellular dehydration, COR15A transitions from a disordered to mostly α-helical structure. We tested whether mutations that increase the helicity o...
Autores principales: | Sowemimo, Oluwakemi T., Knox-Brown, Patrick, Borcherds, Wade, Rindfleisch, Tobias, Thalhammer, Anja, Daughdrill, Gary W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468432/ https://www.ncbi.nlm.nih.gov/pubmed/30832369 http://dx.doi.org/10.3390/biom9030084 |
Ejemplares similares
-
Disorder Predictors Also Predict Backbone Dynamics for a Family of Disordered Proteins
por: Daughdrill, Gary W., et al.
Publicado: (2011) -
Conserved Helix-Flanking Prolines Modulate Intrinsically
Disordered Protein:Target Affinity by Altering the Lifetime of the
Bound Complex
por: Crabtree, Michael D., et al.
Publicado: (2017) -
p53 Phosphomimetics Preserve Transient Secondary Structure but Reduce Binding to Mdm2 and MdmX
por: Levy, Robin, et al.
Publicado: (2019) -
Similar Yet Different–Structural and Functional Diversity among Arabidopsis thaliana LEA_4 Proteins
por: Knox-Brown, Patrick, et al.
Publicado: (2020) -
α-Helix-Mimicking
Sulfono-γ-AApeptide
Inhibitors for p53–MDM2/MDMX Protein–Protein Interactions
por: Sang, Peng, et al.
Publicado: (2020)