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NMDA Receptor Signaling Mediates cFos Expression via Top2β-Induced DSBs in Glioblastoma Cells

The activation of Ca(2+)-permeable N-methyl-D-aspartic acid (NMDA) receptor channels (NMDARs) is crucial for the development and survival of neurons, but many cancers use NMDAR-mediated signaling as well, enhancing the growth and invasiveness of tumors. Thus, NMDAR-dependent pathways emerge as a pro...

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Detalles Bibliográficos
Autores principales: Lutz, Henrik, Nguyen, Thy Anh, Joswig, Juliane, Rau, Kerstin, Laube, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468437/
https://www.ncbi.nlm.nih.gov/pubmed/30841565
http://dx.doi.org/10.3390/cancers11030306

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