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Dysregulation of Macropinocytosis Processes in Glioblastomas May Be Exploited to Increase Intracellular Anti-Cancer Drug Levels: The Example of Temozolomide
Macropinocytosis is a clathrin-independent endocytosis of extracellular fluid that may contribute to cancer aggressiveness through nutrient supply, recycling of plasma membrane and receptors, and exosome internalization. Macropinocytosis may be notably triggered by epidermal growth factor receptor (...
Autores principales: | Colin, Margaux, Delporte, Cédric, Janky, Rekin’s, Lechon, Anne-Sophie, Renard, Gwendoline, Van Antwerpen, Pierre, Maltese, William A., Mathieu, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468498/ https://www.ncbi.nlm.nih.gov/pubmed/30909495 http://dx.doi.org/10.3390/cancers11030411 |
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