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Mechanisms of Antisense Transcription Initiation with Implications in Gene Expression, Genomic Integrity and Disease Pathogenesis

Non-coding antisense transcripts arise from the strand opposite the sense strand. Over 70% of the human genome generates non-coding antisense transcripts while less than 2% of the genome codes for proteins. Antisense transcripts and/or the act of antisense transcription regulate gene expression and...

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Detalles Bibliográficos
Autores principales: Barman, Priyanka, Reddy, Divya, Bhaumik, Sukesh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468509/
https://www.ncbi.nlm.nih.gov/pubmed/30669611
http://dx.doi.org/10.3390/ncrna5010011