Cargando…
Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment
Tumor formation and growth depend on various biological metabolism processes that are distinctly different with normal tissues. Abnormal energy metabolism is one of the typical characteristics of tumors. It has been proven that most tumor cells highly rely on aerobic glycolysis to obtain energy rath...
Autores principales: | Fan, Tengjiao, Sun, Guohui, Sun, Xiaodong, Zhao, Lijiao, Zhong, Rugang, Peng, Yongzhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468516/ https://www.ncbi.nlm.nih.gov/pubmed/30845728 http://dx.doi.org/10.3390/cancers11030317 |
Ejemplares similares
-
Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N’-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study
por: Fan, Tengjiao, et al.
Publicado: (2019) -
Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis
por: Gandham, Srujan Kumar, et al.
Publicado: (2015) -
Identification of the Structural Features of Guanine Derivatives as MGMT Inhibitors Using 3D-QSAR Modeling Combined with Molecular Docking
por: Sun, Guohui, et al.
Publicado: (2016) -
In Silico Prediction of O(6)-Methylguanine-DNA Methyltransferase Inhibitory Potency of Base Analogs with QSAR and Machine Learning Methods
por: Sun, Guohui, et al.
Publicado: (2018) -
Reductive Activity and Mechanism of Hypoxia- Targeted AGT Inhibitors: An Experimental and Theoretical Investigation
por: Xiao, Weinan, et al.
Publicado: (2019)