Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients

Emerin is an essential LEM (LAP2, Emerin, MAN1) domain protein in metazoans and an integral membrane protein associated with inner and outer nuclear membranes. Mutations in the human EMD gene coding for emerin result in the rare genetic disorder: Emery–Dreifuss muscular dystrophy type 1 (EDMD1). Thi...

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Detalles Bibliográficos
Autores principales: Dubińska-Magiera, Magda, Kozioł, Katarzyna, Machowska, Magdalena, Piekarowicz, Katarzyna, Filipczak, Daria, Rzepecki, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468536/
https://www.ncbi.nlm.nih.gov/pubmed/30871242
http://dx.doi.org/10.3390/cells8030240

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