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7-Pyrrolidinethoxy-4′-Methoxyisoflavone Prevents Amyloid β–Induced Injury by Regulating Histamine H3 Receptor-Mediated cAMP/CREB and AKT/GSK3β Pathways

In studies on the treatment of Alzheimer’s disease (AD), in which cognition is enhanced even modestly or selectively, it has been considered that the histamine H3 receptor (H3R) may be a potential target. In this study, we aimed at evaluating the ability of 7-pyrrolidinethoxy-4′-methoxyisoflavone (i...

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Detalles Bibliográficos
Autores principales: Wang, Linlin, Fang, Jiansong, Jiang, Hailun, Wang, Qian, Xue, Situ, Li, Zhuorong, Liu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468582/
https://www.ncbi.nlm.nih.gov/pubmed/31024245
http://dx.doi.org/10.3389/fnins.2019.00334