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7-Pyrrolidinethoxy-4′-Methoxyisoflavone Prevents Amyloid β–Induced Injury by Regulating Histamine H3 Receptor-Mediated cAMP/CREB and AKT/GSK3β Pathways
In studies on the treatment of Alzheimer’s disease (AD), in which cognition is enhanced even modestly or selectively, it has been considered that the histamine H3 receptor (H3R) may be a potential target. In this study, we aimed at evaluating the ability of 7-pyrrolidinethoxy-4′-methoxyisoflavone (i...
Autores principales: | Wang, Linlin, Fang, Jiansong, Jiang, Hailun, Wang, Qian, Xue, Situ, Li, Zhuorong, Liu, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468582/ https://www.ncbi.nlm.nih.gov/pubmed/31024245 http://dx.doi.org/10.3389/fnins.2019.00334 |
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