Development of DNA Aptamers to Native EpCAM for Isolation of Lung Circulating Tumor Cells from Human Blood

We selected DNA aptamers to the epithelial cell adhesion molecule (EpCAM) expressed on primary lung cancer cells isolated from the tumors of patients with non-small cell lung cancer using competitive displacement of aptamers from EpCAM by a corresponding antibody. The resulting aptamers clones showe...

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Detalles Bibliográficos
Autores principales: Zamay, Galina S., Kolovskaya, Olga S., Ivanchenko, Tatiana I., Zamay, Tatiana N., Veprintsev, Dmitry V., Grigorieva, Valentina L., Garanzha, Irina I., Krat, Alexey V., Glazyrin, Yury E., Gargaun, Ana, Lapin, Ivan N., Svetlichnyi, Valery A., Berezovski, Maxim V., Kichkailo, Anna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468627/
https://www.ncbi.nlm.nih.gov/pubmed/30871104
http://dx.doi.org/10.3390/cancers11030351

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