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A Direct Effect of Sex Hormones on Epithelial Barrier Function in Inflammatory Bowel Disease Models

Background: Pregnancy is often described as an immune-tolerant state, and a disease modulatory role for pregnancy on inflammatory bowel disease (IBD) has been suggested. The direct effect of estrogen and progesterone on the intestinal epithelial barrier is underexplored. We investigated the direct c...

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Detalles Bibliográficos
Autores principales: van der Giessen, Janine, van der Woude, C. Janneke, Peppelenbosch, Maikel P., Fuhler, Gwenny M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468635/
https://www.ncbi.nlm.nih.gov/pubmed/30893871
http://dx.doi.org/10.3390/cells8030261

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